Adenosine Kinase Elevation Increases Activity in the Kainic Acid Model of Epilepsy
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چکیده
منابع مشابه
The protective effect of carvacrol on kainic acid-induced model of temporal lobe epilepsy in male rat
Background and Objective: Temporal lobe epilepsy (TLE) is a chronic neurological disorder with spontaneous recurrent seizures and abnormal intracranial waves. Since the role of oxidative stress in the occurrence of epilepsy is inevitable, it seems that the use of antioxidants can prevent some of the complications resulting from this disease. This study was designed to assess the protective effe...
متن کاملInhibition of connexin 36 decreases seizure activity in the Kainic acid-induced rat model of epilepsy
Aim: To investigate the effect of connexin 36-associated (Cx36) channel blockers on the process of epilepsy and its mechanisms. Methods: We examined the anticonvulsant properties of carbenoxolone, quinine, and quinidine in the Kainic Acid-induced (KA-induced) model of epilepsy in rats, and we investigated the effects of these blockers on epileptic discharge and the expression of Cx36. Results: ...
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heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولRole of JNK isoforms in the kainic acid experimental model of epilepsy and neurodegeneration.
Chemoconvulsants that induce status epilepticus in rodents have been widely used over the past decades due to their capacity to reproduce with high similarity neuropathological and electroencephalographic features observed in patients with temporal lobe epilepsy (TLE). Kainic acid is one of the most used chemoconvulsants in experimental models. KA administration mainly induces neuronal loss in...
متن کاملthe protective effect of carvacrol on kainic acid-induced model of temporal lobe epilepsy in male rat
background and objective: temporal lobe epilepsy (tle) is a chronic neurological disorder with spontaneous recurrent seizures and abnormal intracranial waves. since the role of oxidative stress in the occurrence of epilepsy is inevitable, it seems that the use of antioxidants can prevent some of the complications resulting from this disease. this study was designed to assess the protective effe...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2004
ISSN: 1535-7597,1535-7511
DOI: 10.1111/j.1535-7597.2004.04504.x